Transcriptional regulation of the esp genes of enterohemorrhagic Escherichia coli.

@article{Beltrametti1999TranscriptionalRO,
  title={Transcriptional regulation of the esp genes of enterohemorrhagic Escherichia coli.},
  author={Fabrizio Beltrametti and Andreas U. Kresse and Carlos Alberto Guzm{\'a}n},
  journal={Journal of bacteriology},
  year={1999},
  volume={181 11},
  pages={3409-18}
}
We have determined that the genes encoding the secreted proteins EspA, EspD, and EspB of enterohemorrhagic Escherichia coli (EHEC) are organized in a single operon. The esp operon is controlled by a promoter located 94 bp upstream from the ATG start codon of the espA gene. The promoter is activated in the early logarithmic growth phase, upon bacterial contact with eukaryotic cells and in response to Ca2+, Mn2+, and HEPES. Transcription of the esp operon seems to be switched off in tightly… CONTINUE READING