Transcriptional regulation of the Drosophila catalase gene by the DRE/DREF system.

@article{Park2004TranscriptionalRO,
  title={Transcriptional regulation of the Drosophila catalase gene by the DRE/DREF system.},
  author={So Young Park and Young-Shin Kim and Dong-Jin Yang and Mi-Ae Yoo},
  journal={Nucleic acids research},
  year={2004},
  volume={32 4},
  pages={1318-24}
}
Reactive oxygen species (ROS) cause oxidative stress and aging. The catalase gene is a key component of the cellular antioxidant defense network. However, the molecular mechanisms that regulate catalase gene expression are poorly understood. In this study, we have identified a DNA replication-related element (DRE; 5'-TATCGATA) in the 5'-flanking region of… CONTINUE READING