Transcriptional regulation of the Drosophila CycA gene by the DNA replication-related element (DRE) and DRE binding factor (DREF).

@article{Ohno1996TranscriptionalRO,
  title={Transcriptional regulation of the Drosophila CycA gene by the DNA replication-related element (DRE) and DRE binding factor (DREF).},
  author={Kinji Ohno and Fumiko Hirose and Kengo Sakaguchi and Yasuyoshi Nishida and Akio Matsukage},
  journal={Nucleic acids research},
  year={1996},
  volume={24 20},
  pages={3942-6}
}
The Drosophila gene for cyclin A is expressed in dividing cells throughout development. This expression pattern is similar to those of genes related to DNA replication, suggesting involvement of some common control mechanism(s). In the upstream region (-71 to -64 with respect to the transcription initiation site) of the CycA gene, we found a sequence identical to the DNA replication-related element (DRE; 5'-TATCGATA), which is important for high level expression of replication-related genes… CONTINUE READING
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