Transcriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3B.

@article{LaVoie2009TranscriptionalRO,
  title={Transcriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3B.},
  author={Holly A LaVoie and Steven R. King},
  journal={Experimental biology and medicine},
  year={2009},
  volume={234 8},
  pages={
          880-907
        }
}
Expression of the genes that mediate the first steps in steroidogenesis, the steroidogenic acute regulatory protein (STARD1), the cholesterol side-chain cleavage enzyme, cytochrome P450scc (CYP11A1) and 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase (HSD3B), is tightly controlled by a battery of transcription factors in the adrenal cortex, the gonads and the placenta. These genes generally respond to the same hormones that stimulate steroid production through common pathways such as… CONTINUE READING
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