Transcriptional regulation of innate and adaptive lymphocyte lineages.

  title={Transcriptional regulation of innate and adaptive lymphocyte lineages.},
  author={Maria Elena De Obaldia and Avinash Bhandoola},
  journal={Annual review of immunology},
The lymphocyte family has expanded significantly in recent years to include not only the adaptive lymphocytes (T cells, B cells) and NK cells, but also several additional innate lymphoid cell (ILC) types. ILCs lack clonally distributed antigen receptors characteristic of adaptive lymphocytes and instead respond exclusively to signaling via germline-encoded… CONTINUE READING