Transcriptional regulation of fibroblast growth factor-2 expression in human astrocytes: implications for cell plasticity.

@article{Moffett1998TranscriptionalRO,
  title={Transcriptional regulation of fibroblast growth factor-2 expression in human astrocytes: implications for cell plasticity.},
  author={Jennifer Moffett and Erica Kratz and Jeffrey N. Myers and Ewa K. Stachowiak and Robert Z. Florkiewicz and Michal Stachowiak},
  journal={Molecular biology of the cell},
  year={1998},
  volume={9 8},
  pages={2269-85}
}
Induction of the fibroblast growth factor-2 (FGF-2) gene and the consequent accumulation of FGF-2 in the nucleus are operative events in mitotic activation and hypertrophy of human astrocytes. In the brain, these events are associated with cellular degeneration and may reflect release of the FGF-2 gene from cell contact inhibition. We used cultures of human… CONTINUE READING