Transcriptional regulation of brain-derived neurotrophic factor in the amygdala during consolidation of fear memory.

Abstract

We have demonstrated previously that brain-derived neurotrophic factor (BDNF) signaling in the amygdala is required for the consolidation of fear memory. This study is designed to characterize the signal cascades by which fear conditioning modulates transcriptional and translational expression of BDNF. Real-time reverse transcription-coupled polymerase… (More)

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