Transcriptional regulation of HLA-G.

@article{Gobin1999TranscriptionalRO,
  title={Transcriptional regulation of HLA-G.},
  author={Sam J. P. Gobin and Vivian Keijsers and Cheolho Cheong and Moniek van Zutphen and Peter J. van den Elsen},
  journal={Transplantation proceedings},
  year={1999},
  volume={31 4},
  pages={
          1857-9
        }
}
  • Sam J. P. Gobin, Vivian Keijsers, +2 authors Peter J. van den Elsen
  • Published in Transplantation proceedings 1999
  • Biology, Medicine
  • THE EXPRESSION of HLA class I molecules is essential in the immune response, as they present antigenderived peptides to cytotoxic T lymphocytes. The classical HLA class I genes (HLA-A, HLA-B, and HLA-C) are highly polymorphic and are ubiquitously expressed on most somatic cells. The nonclassical HLA class I molecules (HLA-E, HLA-F, and HLA-G) have a limited polymorphism and display a restricted expression pattern. In this respect, the expression of HLA-G is confined to extravillous… CONTINUE READING

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