Transcriptional regulation by the numbers: models.


The expression of genes is regularly characterized with respect to how much, how fast, when and where. Such quantitative data demands quantitative models. Thermodynamic models are based on the assumption that the level of gene expression is proportional to the equilibrium probability that RNA polymerase (RNAP) is bound to the promoter of interest… (More)


4 Figures and Tables

Cite this paper

@article{Bintu2005TranscriptionalRB, title={Transcriptional regulation by the numbers: models.}, author={Lacramioara Bintu and Nicolas E Buchler and Hernan G. Garcia and Ulrich Gerland and Terence Hwa and Jan{\'e} Kondev and Rob Phillips}, journal={Current opinion in genetics & development}, year={2005}, volume={15 2}, pages={116-24} }