Transcriptional regulation by histone modifications: towards a theory of chromatin re-organization during stem cell differentiation.

@article{Binder2013TranscriptionalRB,
  title={Transcriptional regulation by histone modifications: towards a theory of chromatin re-organization during stem cell differentiation.},
  author={Hans Binder and Lydia Steiner and Jens Przybilla and Thimo Rohlf and Sonja J. Prohaska and Joerg Galle},
  journal={Physical biology},
  year={2013},
  volume={10 2},
  pages={026006}
}
Chromatin-related mechanisms, as e.g. histone modifications, are known to be involved in regulatory switches within the transcriptome. Only recently, mathematical models of these mechanisms have been established. So far they have not been applied to genome-wide data. We here introduce a mathematical model of transcriptional regulation by histone… CONTINUE READING