Transcriptional regulation by a naturally occurring truncated rat estrogen receptor (ER), truncated ER product-1 (TERP-1).

@article{Schreihofer1999TranscriptionalRB,
  title={Transcriptional regulation by a naturally occurring truncated rat estrogen receptor (ER), truncated ER product-1 (TERP-1).},
  author={Derek A. Schreihofer and Eileen M Resnick and Andrew Y Soh and Margaret A. Shupnik},
  journal={Molecular endocrinology},
  year={1999},
  volume={13 2},
  pages={320-9}
}
Truncated estrogen receptor product-1 (TERP-1) is a naturally occurring rat estrogen receptor (ER) variant transcribed from a unique start site and containing a unique 5'-untranslated region fused to exons 5-8 of ERalpha. TERP-1 is detected only in the pituitary, and TERP-1 mRNA levels are highly regulated during the estrous cycle, exceeding those of the full-length ERalpha on proestrus. These data suggest that TERP-1 may play a role in estrogen- regulated feedback in the pituitary. We examined… CONTINUE READING