Transcriptional programming of tissue-resident memory CD8+ T cells.

Abstract

Tissue-resident memory CD8+ T cells (TRM) are localized in non-lymphoid tissues throughout the body where they mediate long-lived protective immunity at common sites of pathogen exposure. As the signals controlling TRM differentiation are uncovered, it is becoming apparent that the dynamic activities of numerous transcription factors are intricately… (More)
DOI: 10.1016/j.coi.2018.03.017

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