Transcriptional profiling reveals a possible role for the timing of the inflammatory response in determining susceptibility to a viral infection.

@article{Ruby2006TranscriptionalPR,
  title={Transcriptional profiling reveals a possible role for the timing of the inflammatory response in determining susceptibility to a viral infection.},
  author={Thomas Ruby and Catherine A. Whittaker and David R Withers and Mounira K Chelbi-alix and V{\'e}ronique Morin and Anne Oudin and John Young and Rima Zoorob},
  journal={Journal of virology},
  year={2006},
  volume={80 18},
  pages={9207-16}
}
Using a novel cDNA microarray prepared from sources of actively responding immune system cells, we have investigated the changes in gene expression in the target tissue during the early stages of infection of neonatal chickens with infectious bursal disease virus. Infections of two lines of chickens previously documented as genetically resistant and sensitive to infection were compared in order to ascertain early differences in the response to infection that might provide clues to the mechanism… CONTINUE READING