Transcriptional profiling of human osteoblast differentiation.

@article{Billiard2003TranscriptionalPO,
  title={Transcriptional profiling of human osteoblast differentiation.},
  author={Julia Billiard and Robert A. Moran and Maryann Z Whitley and Moitreyee Chatterjee-Kishore and Karen Gillis and Eugene L. Brown and Barry S. Komm and Peter V. N. Bodine},
  journal={Journal of cellular biochemistry},
  year={2003},
  volume={89 2},
  pages={389-400}
}
Osteoblast differentiation is a key aspect of bone formation and remodeling. To further our understanding of the differentiation process, we have developed a collection of conditionally immortalized adult human osteoblast cell lines representing discrete stages of differentiation. To evaluate changes in gene expression associated with differentiation, polyA((+)) RNA from pre-osteoblasts, early and late osteoblasts, and pre-osteocytes was subjected to gene chip analysis using the Affymetrix… CONTINUE READING

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