Transcriptional profiling of human osteoblast differentiation.

  title={Transcriptional profiling of human osteoblast differentiation.},
  author={Julia Billiard and Robert A. Moran and Maryann Z Whitley and Moitreyee Chatterjee-Kishore and Karen Gillis and Eugene L. Brown and Barry S. Komm and Peter V. N. Bodine},
  journal={Journal of cellular biochemistry},
  volume={89 2},
Osteoblast differentiation is a key aspect of bone formation and remodeling. To further our understanding of the differentiation process, we have developed a collection of conditionally immortalized adult human osteoblast cell lines representing discrete stages of differentiation. To evaluate changes in gene expression associated with differentiation, polyA((+)) RNA from pre-osteoblasts, early and late osteoblasts, and pre-osteocytes was subjected to gene chip analysis using the Affymetrix… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 23 extracted citations

The MET oncogene transforms human primary bone-derived cells into osteosarcomas by targeting committed osteo-progenitors.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • 2012
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…