Transcriptional profiling of human embryonic stem cells differentiating to definitive and primitive endoderm and further toward the hepatic lineage.

@article{Synnergren2010TranscriptionalPO,
  title={Transcriptional profiling of human embryonic stem cells differentiating to definitive and primitive endoderm and further toward the hepatic lineage.},
  author={Jane Synnergren and Nico Heins and Gabriella Brol{\'e}n and Gustav Eriksson and Anders H Lindahl and Johan Hyllner and B. Olsson and Peter Sartipy and Petter Bj{\"o}rquist},
  journal={Stem cells and development},
  year={2010},
  volume={19 7},
  pages={961-78}
}
Human embryonic stem cells (hESC) can differentiate into a variety of specialized cell types, and they constitute a useful model system to study embryonic development in vitro. In order to fully utilize the potential of these cells, the mechanisms that regulate the developmental processes of specific lineage differentiation need to be better defined. The aim of this study was to explore the molecular program involved in the differentiation of hESC toward definitive endoderm (DE) and further… CONTINUE READING

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