Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells.

Abstract

Inflammatory stimulation of endothelial cells by tumor necrosis factor alpha (TNF-alpha) involves activation of nuclear factor kappa B (NF-kappa B) and p38 mitogen-activated protein (MAP) kinase signaling pathways. A reliable analysis of the gene expression program elicited by TNF-alpha and its assignment to distinct signaling pathways is not available. A… (More)

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@article{Viemann2004TranscriptionalPO, title={Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells.}, author={Dorothee Viemann and Matthias Goebeler and Sybille Schmid and Kerstin Klimmek and Clemens Sorg and Stephan Ludwig and Johannes Roth}, journal={Blood}, year={2004}, volume={103 9}, pages={3365-73} }