Transcriptional profiling analysis and functional prediction of long noncoding RNAs in cancer

@inproceedings{Yuan2016TranscriptionalPA,
  title={Transcriptional profiling analysis and functional prediction of long noncoding RNAs in cancer},
  author={Jiao Yuan and Haiyan Yue and Meiying Zhang and Jianjun Luo and Lihui Liu and Wei Wu and Tengfei Xiao and Xiaowei Chen and Xiaomin Chen and Dongdong Zhang and Rui Xing and Xin Tong and Nan Wu and Jian Zhao and Youyong Lu and Mingzhou Guo and Runsheng Chen},
  booktitle={Oncotarget},
  year={2016}
}
Long noncoding RNAs (lncRNAs), which are noncoding RNAs (ncRNAs) with length more than 200 nucleotides (nt), have been demonstrated to be involved in various types of cancer. Consequently, it has been frequently discussed that lncRNAs with aberrant expression in cancer serve as potential diagnostic biomarkers and therapeutic targets. However, one major challenge of developing cancer biomarkers is tumor heterogeneity which means that tumor cells show different cellular morphology, metastatic… CONTINUE READING
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