Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica

@article{LpezCasamichana2007TranscriptionalPO,
  title={Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica},
  author={Mavil L{\'o}pez-Casamichana and Esther Orozco and Laurence A. Marchat and C{\'e}sar L{\'o}pez-Camarillo},
  journal={BMC Molecular Biology},
  year={2007},
  volume={9},
  pages={35 - 35}
}
In eukaryotic and prokaryotic cells, homologous recombination is an accurate mechanism to generate genetic diversity, and it is also used to repair DNA double strand-breaks. RAD52 epistasis group genes involved in recombinational DNA repair, including mre11, rad50, nsb1/xrs2, rad51, rad51c/rad57, rad51b/rad55, rad51d, xrcc2, xrcc3, rad52, rad54, rad54b/rdh54 and rad59 genes, have been studied in human and yeast cells. Notably, the RAD51 recombinase catalyses strand transfer between a broken DNA… CONTINUE READING