Transcriptional network of androgen receptor in prostate cancer progression

@article{Takayama2013TranscriptionalNO,
  title={Transcriptional network of androgen receptor in prostate cancer progression},
  author={Ken-Ichi Takayama and Satoshi Inoue},
  journal={International Journal of Urology},
  year={2013},
  volume={20}
}
The androgen receptor belongs to the nuclear receptor superfamily and functions as a ligand‐dependent transcription factor. It binds to the androgen responsive element and recruits coregulatory factors to modulate gene transcription. In addition, the androgen receptor interacts with other transcription factors, such as forkhead box A1, and other oncogenic signaling pathway molecules that bind deoxyribonucleic acid and regulate transcription. Androgen receptor signaling plays an important role… Expand
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