Transcriptional integration of mitochondrial biogenesis

@article{Scarpulla2012TranscriptionalIO,
  title={Transcriptional integration of mitochondrial biogenesis},
  author={R. Scarpulla and R. Vega and D. Kelly},
  journal={Trends in Endocrinology \& Metabolism},
  year={2012},
  volume={23},
  pages={459-466}
}
Gene regulatory factors encoded by the nuclear genome are essential for mitochondrial biogenesis and function. Some of these factors act exclusively within the mitochondria to regulate the control of mitochondrial transcription, translation, and other functions. Others govern the expression of nuclear genes required for mitochondrial metabolism and organelle biogenesis. The peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1) family of transcriptional coactivators play a major… Expand
Mitochondrial biogenesis through activation of nuclear signaling proteins.
Nuclear Transcription Factors in the Mitochondria: A New Paradigm in Fine-Tuning Mitochondrial Metabolism.
Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function
Regulation of mitochondrial biogenesis and PGC-1α under cellular stress.
  • T. Wenz
  • Biology, Medicine
  • Mitochondrion
  • 2013
Transcription, Processing, and Decay of Mitochondrial RNA in Health and Disease
Role of NCoR1 in mitochondrial function and energy metabolism
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 275 REFERENCES
Nuclear activators and coactivators in mammalian mitochondrial biogenesis.
  • R. Scarpulla
  • Biology, Medicine
  • Biochimica et biophysica acta
  • 2002
Nuclear Control of Respiratory Chain Expression in Mammalian Cells
  • R. Scarpulla
  • Biology, Medicine
  • Journal of bioenergetics and biomembranes
  • 1997
Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis.
...
1
2
3
4
5
...