Transcriptional induction of repair genes during slowing of replication in irradiated Saccharomyces cerevisiae.

@article{Mercier2001TranscriptionalIO,
  title={Transcriptional induction of repair genes during slowing of replication in irradiated Saccharomyces cerevisiae.},
  author={Ginette Mercier and Yann Denis and Philippe Marc and Laurent Picard and Marie Dutreix},
  journal={Mutation research},
  year={2001},
  volume={487 3-4},
  pages={157-72}
}
We investigated the inhibition of cell-cycle progression and replication and the induction of the transcriptional response in diploid budding yeast populations exposed to two different doses of gamma-rays resulting in 15 and 85% survival respectively. We studied the kinetics of the cellular response to ionizing treatment during the period required for all of the surviving cells to achieve at least one cell division. The length of these periods increased with the dose. Irradiated populations… CONTINUE READING

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