Transcriptional elongation of c-myb is regulated by NF-kappaB (p50/RelB).

  title={Transcriptional elongation of c-myb is regulated by NF-kappaB (p50/RelB).},
  author={Modem Suhasini and Renate B Pilz},
  volume={18 51},
High levels of c-myb expression are necessary for the proliferation of hematopoietic precursor cells whereas down-regulation of c-myb is required for terminal differentiation; this down-regulation occurs through a conditional block to transcriptional elongation in intron I. We previously observed that cAMP analogs prevented the late down-regulation of c-myb during hexamethylene bisacetamide (HMBA)-induced differentiation of murine erythroleukemia (MEL) cells and blocked differentiation; this… CONTINUE READING
13 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…