Transcriptional downregulation of DC-SIGN in human herpesvirus 6-infected dendritic cells.

@article{Niiya2004TranscriptionalDO,
  title={Transcriptional downregulation of DC-SIGN in human herpesvirus 6-infected dendritic cells.},
  author={Hironari Niiya and Taichi Azuma and Lei Jin and Naoyuki Uchida and Atsushi Inoue and Hitoshi Hasegawa and Shigeru Fujita and Mikiko Tohyama and Koji Hashimoto and Masaki Yasukawa},
  journal={The Journal of general virology},
  year={2004},
  volume={85 Pt 9},
  pages={2639-42}
}
DC-SIGN expressed on dendritic cells (DCs) efficiently binds and transmits various pathogens, including human immunodeficiency virus, to lymphoid tissues and permissive cells. Consequently, alteration of DC-SIGN expression may affect susceptibility and resistance to pathogens. The present study shows that infection with human herpesvirus 6 (HHV-6) induces downregulation of DC-SIGN expression on immature DCs. Expression levels of DC-SIGN mRNA and intracellular protein appeared to decrease… CONTINUE READING
Highly Cited
This paper has 33 citations. REVIEW CITATIONS
9 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…