Transcriptional control of the human plasma membrane phospholipid scramblase 1 gene is mediated by interferon-alpha.

@article{Zhou2000TranscriptionalCO,
  title={Transcriptional control of the human plasma membrane phospholipid scramblase 1 gene is mediated by interferon-alpha.},
  author={Quansheng Zhou and Ji'en Zhao and Fahad al-Zoghaibi and Anyu Zhou and Therese Wiedmer and Robert H. Silverman and Peter J. Sims},
  journal={Blood},
  year={2000},
  volume={95 8},
  pages={2593-9}
}
Interferons (IFNs) mediate their diverse biologic activities through induction of the expression of multiple genes. Whereas the mode of action of certain of these IFN-regulated genes has been well characterized, most of the molecular and cellular events underlying the constellation of biologic responses to the IFNs remain unresolved. This study showed that the newly identified PLSCR1 gene for phospholipid scramblase, previously implicated in remodeling of plasma membrane phospholipids, is… CONTINUE READING

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