Transcriptional control of terminal nephron differentiation.

  title={Transcriptional control of terminal nephron differentiation.},
  author={Samir S. El-Dahr and Karam Aboudehen and Zubaida Saifudeen},
  journal={American journal of physiology. Renal physiology},
  volume={294 6},
Terminal differentiation of epithelial cells into more specialized cell types is a critical step in organogenesis. Throughout the process of terminal differentiation, epithelial progenitors acquire or upregulate expression of renal function genes and cease to proliferate, while expression of embryonic genes is repressed. This exquisite coordination of gene expression is accomplished by signaling networks and transcription factors which couple the external environment with the new functional… CONTINUE READING
13 Citations
79 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 13 extracted citations


Publications referenced by this paper.
Showing 1-10 of 79 references

Interplay between the tumor suppres Invited Review F1277 RENAL EPITHELIAL CELL DIFFERENTIATION AJP-Renal Physiol

  • K Takebayashi-Suzuki, J Funami, +5 authors A. Suzuki
  • Development 130:
  • 2008
1 Excerpt

Similar Papers

Loading similar papers…