Transcriptional control of cognitive development.

@article{Hong2005TranscriptionalCO,
  title={Transcriptional control of cognitive development.},
  author={Elizabeth J. Hong and Anne E West and Michael E. Greenberg},
  journal={Current opinion in neurobiology},
  year={2005},
  volume={15 1},
  pages={21-8}
}
Cognitive development is determined by both genetics and environment. One point of convergence of these two influences is the neural activity-dependent regulation of programs of gene expression that specify neuronal fate and function. Human genetic studies have linked several transcriptional regulators to neurodevelopmental disorders including mental retardation and autism spectrum disorders. Recent reports on two such factors, CREB-binding protein and methyl-CpG-binding protein 2, have begun… CONTINUE READING

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