Transcriptional control of RfaH on polysialic and colanic acid synthesis by Escherichia coli K92.

@article{Navasa2014TranscriptionalCO,
  title={Transcriptional control of RfaH on polysialic and colanic acid synthesis by Escherichia coli K92.},
  author={Nicol{\'a}s Navasa and Leandro b. Rodr{\'i}guez-aparicio and Miguel {\'A}ngel Ferrero and Andrea Monteagudo-Mera and Honorina Mart{\'i}nez-blanco},
  journal={FEBS letters},
  year={2014},
  volume={588 6},
  pages={922-8}
}
The transcriptional antiterminator RfaH promotes transcription of long operons encoding surface cell components important for the virulence of Escherichiacoli pathogens. In this paper, we show that RfaH enhanced kps expression for the synthesis of group 2 polysialic acid capsule in E. coli K92. In addition, we demonstrate for the first time that RfaH promotes cps expression for the synthesis of colanic acid, a cell wall component with apparently no role on pathogenicity. Finally, we show a… CONTINUE READING
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