Transcriptional changes in rat α-motoneurons resulting from increased physical activity

@article{Woodrow2013TranscriptionalCI,
  title={Transcriptional changes in rat α-motoneurons resulting from increased physical activity},
  author={Lawrence Kevin Woodrow and Philippa Sheppard and Phillip F. Gardiner},
  journal={Neuroscience},
  year={2013},
  volume={255},
  pages={45-54}
}
Electrophysiological properties of lumbar α-motoneurons change after chronic increases and decreases in hindlimb neuromuscular activity. Although modeling of these changes suggests that motoneurons probably alter gene expression in these situations, there is no evidence that this is the case. In this study, we measured the content of several mRNAs in lumbar motoneurons, harvested using laser capture microdissection, from rats previously subjected to normal cage activity, voluntary wheel… CONTINUE READING

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