Transcriptional antitermination

@article{Greenblatt1993TranscriptionalA,
  title={Transcriptional antitermination},
  author={Jack Greenblatt and Justin R Nodwell and Stephen W. Mason},
  journal={Nature},
  year={1993},
  volume={364},
  pages={401-406}
}
Antiterminator proteins control gene expression by recognizing control signals near the promoter and preventing transcriptional termination which would otherwise occur at sites that may be a long way downstream. The N protein of bacteriophage λ recognizes a sequence in the nascent RNA, and modifies RNA polymerase by catalysing the formation of a stable ribonucleo-protein complex on its surface, whereas the λ Q protein recognizes a sequence in the DNA. These mechanisms of antitermination in… CONTINUE READING
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