Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney

Abstract

We investigated the effects on urinary steroid and electrolyte excretion and renal gene expression of chronic infusions of ACTH in the mouse. ACTH caused a sustained increase in corticosteroid excretion; aldosterone excretion was only transiently elevated. There was an increase in the excretion of deoxycorticosterone, a weak mineralocorticoid, to levels of… (More)
DOI: 10.1152/physiolgenomics.00088.2009

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@inproceedings{Dunbar2010TranscriptionalAP, title={Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney}, author={Donald R. Dunbar and Hiba Khaled and Louise C. Evans and Emad A. S. Al-Dujaili and Linda J Mullins and John J. Mullins and Christopher J. Kenyon and M A Bailey}, booktitle={Physiological genomics}, year={2010} }