Transcriptional and Translational Regulation of Stem Cells

@inproceedings{Hime2013TranscriptionalAT,
  title={Transcriptional and Translational Regulation of Stem Cells},
  author={Gary R Hime and Helen Abud},
  booktitle={Advances in Experimental Medicine and Biology},
  year={2013}
}
This volume describes the latest fi ndings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches… CONTINUE READING
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