Transcriptional analysis of the titin cap gene

@article{Zhang2011TranscriptionalAO,
  title={Transcriptional analysis of the titin cap gene},
  author={Shuang Zhang and Priya V. Londhe and Mei-Ling Zhang and Judith Davie},
  journal={Molecular Genetics and Genomics},
  year={2011},
  volume={285},
  pages={261-272}
}
Mutations in titin cap (Tcap), also known as telethonin, cause limb-girdle muscular dystrophy type 2G (LGMD2G). Tcap is one of the titin interacting Z-disc proteins involved in the regulation and development of normal sarcomeric structure. Given the essential role of Tcap in establishing and maintaining normal skeletal muscle architecture, we were interested in determining the regulatory elements required for expression of this gene in myoblasts. We have defined a highly conserved 421 bp… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Similar Papers

Loading similar papers…