Transcriptional analysis of the queD gene coding for quercetinase of Streptomyces sp. FLA.

@article{Merkens2008TranscriptionalAO,
  title={Transcriptional analysis of the queD gene coding for quercetinase of Streptomyces sp. FLA.},
  author={Hedda Merkens and Susanne Fetzner},
  journal={FEMS microbiology letters},
  year={2008},
  volume={287 1},
  pages={100-7}
}
Quercetinase, catalyzing the 2,4-dioxygenolytic cleavage of the flavonol quercetin (3,5,7,3',4'-pentahydroxyflavone) to carbon monoxide and 2-protocatechuoylphloroglucinol carboxylic acid, is encoded by the queD gene in Streptomyces sp. FLA. Because studies on the transcriptional regulation of quercetinase genes are rare, we analyzed the expression of queD in response to quercetin and other carbon compounds. RNA hybridization experiments revealed that transcription of queD is triggered by… CONTINUE READING