Transcriptional analysis of the Streptococcus mutans hrcA, grpE and dnaK genes and regulation of expression in response to heat shock and environmental acidification.

@article{Jayaraman1997TranscriptionalAO,
  title={Transcriptional analysis of the Streptococcus mutans hrcA, grpE and dnaK genes and regulation of expression in response to heat shock and environmental acidification.},
  author={Gopalswamy Jayaraman and Julie Penders and Robert A Burne},
  journal={Molecular microbiology},
  year={1997},
  volume={25 2},
  pages={329-41}
}
The dental pathogen Streptococcus mutans persists and causes diseases in highly dynamic environments and gains a selective ecological advantage in environmental conditions that frequently exceed the limits for growth of the organism, particularly with regard to environmental pH. The goal of this study was to begin a molecular genetic analysis of a major stress protein, DnaK/Hsp70, to begin to understand how stress responses are regulated in this lactic acid bacterium and to establish a… CONTINUE READING

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