Transcriptional analysis of rat photoreceptor cells reveals daily regulation of genes important for visual signaling and light damage susceptibility.

@article{Kunst2013TranscriptionalAO,
  title={Transcriptional analysis of rat photoreceptor cells reveals daily regulation of genes important for visual signaling and light damage susceptibility.},
  author={Stefanie Kunst and Tanja Wolloscheck and Philip H{\"o}lter and Alexander Wengert and Markus Grether and Carsten Sticht and Veronika Weyer and Uwe Wolfrum and Rainer Spessert},
  journal={Journal of neurochemistry},
  year={2013},
  volume={124 6},
  pages={757-69}
}
Photoreceptor cells face the challenge of adjusting their function and, possibly, their susceptibility to light damage to the marked daily changes in ambient light intensity. To achieve a better understanding of photoreceptor adaptation at the transcriptional level, this study aimed to identify genes which are under daily regulation in photoreceptor cells using microarray analysis and quantitative PCR. Included in the gene set obtained were a number of genes which up until now have not been… CONTINUE READING
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