Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content.

@article{Keller2001TranscriptionalAO,
  title={Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content.},
  author={Charlotte Keller and Adam Steensberg and Henriette Pilegaard and Takuya Osada and Bengt Saltin and Bente Klarlund Pedersen and P. Darrell Neufer},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2001},
  volume={15 14},
  pages={2748-50}
}
In humans, the plasma interleukin 6 (IL-6) concentration increases dramatically during low-intensity exercise. Measurements across the working limb indicate that skeletal muscle is the source of IL-6 production. To determine whether energy availability influences the regulation of IL-6 expression during prolonged exercise, six male subjects completed two trials consisting of 180 min of two-legged dynamic knee extensor with either normal or low (~60% of control) pre-exercise muscle glycogen… CONTINUE READING
Highly Influential
This paper has highly influenced a number of papers. REVIEW HIGHLY INFLUENTIAL CITATIONS