Transcriptional activation of the H-ferritin gene in differentiated Caco-2 cells parallels a change in the activity of the nuclear factor Bbf.

@article{Bevilacqua1995TranscriptionalAO,
  title={Transcriptional activation of the H-ferritin gene in differentiated Caco-2 cells parallels a change in the activity of the nuclear factor Bbf.},
  author={Maria Assunta Bevilacqua and Maria Concetta Faniello and Paul D'Agostino and Barbara Quaresima and Maria Teresa Tiano and Sandro Pignata and Tommaso Russo and Filiberto Cimino and Francesco Costanzo},
  journal={The Biochemical journal},
  year={1995},
  volume={311 ( Pt 3)},
  pages={769-73}
}
In this paper, we examine the mechanisms that regulate the expression of the heavy (H) ferritin subunit in the colon carcinoma Caco-2 cell line allowed to differentiate spontaneously in vitro. The differentiation process of these cells in continuous culture is accompanied by an accumulation of the mRNA coding for the apoferritin H chain. The analysis of… CONTINUE READING