Transcriptional activation: risky business.

@article{Tansey2001TranscriptionalAR,
  title={Transcriptional activation: risky business.},
  author={William P Tansey},
  journal={Genes & development},
  year={2001},
  volume={15 9},
  pages={
          1045-50
        }
}
Transcriptional regulation is all about getting RNA polymerase to the right place on the gene at the right time and making sure that it is competent to conduct transcription. Traditional views of this process place most of their emphasis on the events that precede initiation of transcription. We imagine a promoter-bound transcriptional activator (or collection of activators) recruiting components of the basal transcriptional machinery to the DNA, eventually leading to the recruitment of RNA… CONTINUE READING

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Negative regulation

  • S. A. Carr, R. J. Deshaies
  • 2001

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