Transcriptional Regulation of Human and Hamster Microsomal Triglyceride Transfer Protein Genes

@inproceedings{Hagan2001TranscriptionalRO,
  title={Transcriptional Regulation of Human and Hamster Microsomal Triglyceride Transfer Protein Genes},
  author={Deborah L. Hagan and Bernadette K. Kienzle and Haris Bin Jamil and Narayanan HariharanS},
  year={2001}
}
In order to characterize the molecular mechanisms that dictate microsomal triglyceride transfer protein (MTP) gene transcription in human and hamster, two species with similar plasma lipoprotein profiles, the MTP gene promoters were cloned, sequenced, and functionally characterized by transient transfection analysis. The results presented in this report indicate that the 5' ends of human and hamster MTP genes share similar structural features. The promoter sequences are well conserved and… CONTINUE READING

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The role of microsomal triglyceride transfer protein in lipoprotein assembly: an update.

  • Frontiers in bioscience : a journal and virtual library
  • 2003
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