Transcriptional Regulation: Cancer, Neurons and the REST

@article{Coulson2005TranscriptionalRC,
  title={Transcriptional Regulation: Cancer, Neurons and the REST},
  author={J. Coulson},
  journal={Current Biology},
  year={2005},
  volume={15},
  pages={R665-R668}
}
  • J. Coulson
  • Published 2005
  • Medicine, Biology
  • Current Biology
  • REST/NRSF was first identified as a transcriptional repressor of neuronal genes in non-neuronal cells. Recent studies have now revealed seemingly paradoxical roles for REST/NRSF in neurogenesis, neural plasticity, tumour suppression and cancer progression. 

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