Transcriptional Dissection of Human Limbal Niche Compartments by Massive Parallel Sequencing

@inproceedings{Bath2013TranscriptionalDO,
  title={Transcriptional Dissection of Human Limbal Niche Compartments by Massive Parallel Sequencing},
  author={Chris Bath and Danson Vasanthan Muttuvelu and Jeppe Emmersen and Henrik Vorum and Jesper {\O}stergaard Hjortdal and Vladimir Zachar},
  booktitle={PloS one},
  year={2013}
}
Corneal epithelium is maintained throughout life by well-orchestrated proliferation of limbal epithelial stem cells (LESCs), followed by migration and maturation centripetally towards the ocular surface. Disturbance of LESCs can potentially lead to a blinding condition, which can be reversed by reconstitution of a functional LESC pool. The current clinical procedures are effective to some degree, however, deeper knowledge of the molecular interplay within the limbal niche is necessary to… CONTINUE READING
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An Insight into the Difficulties in the Discovery of Specific Biomarkers of Limbal Stem Cells

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  • 2018
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References

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SHOWING 1-10 OF 75 REFERENCES

Dependence of corneal stem/progenitor cells on ocular surface innervation.

  • Investigative ophthalmology & visual science
  • 2012
VIEW 1 EXCERPT

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