Transcriptional Analysis of Temporal Gene Expression in Germinating Clostridium difficile 630 Endospores


Clostridium difficile is the leading cause of hospital acquired diarrhoea in industrialised countries. Under conditions that are not favourable for growth, the pathogen produces metabolically dormant endospores via asymmetric cell division. These are extremely resistant to both chemical and physical stress and provide the mechanism by which C. difficile can… (More)
DOI: 10.1371/journal.pone.0064011


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