Transcription termination and anti‐termination in E. coli

@article{Nudler2002TranscriptionTA,
  title={Transcription termination and anti‐termination in E. coli},
  author={Evgeny Nudler and Max E. Gottesman},
  journal={Genes to Cells},
  year={2002},
  volume={7}
}
Transcription termination in Escherichia coli is controlled by many factors. The sequence of the DNA template, the structure of the transcript, and the actions of auxiliary proteins all play a role in determining the efficiency of the process. Termination is regulated and can be enhanced or suppressed by host and phage proteins. This complex reaction is rapidly yielding to biochemical and structural analysis of the interacting factors. Below we review and attempt to unify into basic principles… 
The role of E. coli Nus-Factors in transcription regulation and transcription
TLDR
The structural interplay and the mechanistic role of the Nus-factors that are directly involved in processive elongation, transcription:translation coupling and termination as well as the varying effects of these proteins on transcription under the influence of additional signals are discussed.
Control of Transcription Termination and Antitermination
TLDR
The regulatory molecules that are known to influence the elongation/termination decision by RNA polymerase (RNAP) are described, with the emphasis on the most recent findings and on the mechanism of ‘‘active’’ regulators whose actions are not limited to changes in RNA folding.
Transcription termination by nuclear RNA polymerases.
TLDR
The present state of knowledge on how each of the three RNA polymerases terminates and how mechanisms are conserved, or vary, from yeast to human is described.
Suppression of Factor-Dependent TranscriptionTermination by AntiterminatorRNA
TLDR
Nascent transcripts of the phage HK022 put sites modify the transcription elongation complex so that it terminates less efficiently at intrinsic transcription terminators and accelerates through pause sites, suggesting that put inhibits a step that is common to termination at the different types of terminator.
Regulation of Transcription Elongation and Termination
TLDR
Why transcription elongation complexes pause at certain template sites and how auxiliary host and phage transcription factors affect elongation and termination in E. coli are discussed.
Mechanism of Action of Bacterial Transcription Terminator Rho
TLDR
This review includes the biochemistry and the structural analyses of the Rho, its mechanism of action, its regulation by other cellular factors and briefly cellular events controlled by this protein.
sRNA-Mediated Control of Transcription Termination in E. coli
Loading Rho to Terminate Transcription
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