Transcription repression and blocks in cell cycle progression in hypoplastic left heart syndrome.

@article{Gambetta2008TranscriptionRA,
  title={Transcription repression and blocks in cell cycle progression in hypoplastic left heart syndrome.},
  author={Katheryn E. Gambetta and Mohamad K Al-Ahdab and Michel N. Ilbawi and Nahidh Hassaniya and M. V. N. V. Prasad Gupta},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2008},
  volume={294 5},
  pages={H2268-75}
}
Hypoplastic left heart syndrome (HLHS) is characterized by abnormally developed atrial septum and a severe underdevelopment of the left side of the heart. Despite significant advances in its surgical management, little is known about the molecular abnormalities in this syndrome. To gain molecular insights into HLHS, expression profiling by gene-chip microarray (Affymetrix U133 2.0) and by real-time RT-PCR was performed in the atrial septum of patients diagnosed with HLHS and compared with age… CONTINUE READING
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