Transcription regulation and human diseases.

  title={Transcription regulation and human diseases.},
  author={Jean Villard},
  journal={Swiss medical weekly},
  volume={134 39-40},
Regulation of gene expression is a crucial step in the maintenance of cellular homeostasis. The control of gene expression can occur in multiple steps. The overwhelming majority of regulatory events occur at the level of transcription. To initiate transcription eukaryotic polymerase RNA II requires the close collaboration of a battery of proteins collectively termed transcription factors. Transcription factors are generally divided into two groups: (1) the basal transcription factors which are… CONTINUE READING
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