Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast.

@article{Aslanzadeh2018TranscriptionRS,
  title={Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast.},
  author={Vahid Aslanzadeh and Yuanhua Huang and G. Sanguinetti and Jean D. Beggs},
  journal={Genome research},
  year={2018},
  volume={28 2},
  pages={
          203-213
        }
}
The functional consequences of alternative splicing on altering the transcription rate have been the subject of intensive study in mammalian cells but less is known about effects of splicing on changing the transcription rate in yeast. We present several lines of evidence showing that slow RNA polymerase II elongation increases both cotranscriptional… CONTINUE READING