Transcription program of human herpesvirus 8 (kaposi's sarcoma-associated herpesvirus).

@article{PauloseMurphy2001TranscriptionPO,
  title={Transcription program of human herpesvirus 8 (kaposi's sarcoma-associated herpesvirus).},
  author={Mini Paulose-Murphy and Nan Kyung Ha and C Xiang and Yalu Chen and L A Gillim and Robert Yarchoan and Paul G Meltzer and Mauricio Bittner and Jeffery Trent and Steven Zeichner},
  journal={Journal of virology},
  year={2001},
  volume={75 10},
  pages={4843-53}
}
Human herpesvirus 8 (HHV-8), a gammaherpesvirus implicated in Kaposi's sarcoma, primary effusion lymphoma, and Castleman's disease, encodes several pathogenically important cellular homologs. To define the HHV-8 transcription program, RNA obtained from latently infected body cavity-based lymphoma 1 cells induced to undergo lytic replication was used to query a custom HHV-8 DNA microarray containing nearly every known viral open reading frame. The patterns of viral gene expression offer insights… CONTINUE READING
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