Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition.

  title={Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition.},
  author={Andr{\'e} M. Nantel and Daniel Dignard and Catherine L. Bachewich and Doreen Harcus and Anne Marcil and Anne-Pascale Bouin and Christoph Sensen and Herv{\'e} Hogues and Marco van het Hoog and Paul Gordon and Tracey Rigby and François Benoit and Daniel C. Tessier and David Y. Thomas and Malcolm Whiteway},
  journal={Molecular biology of the cell},
  volume={13 10},
The ability of the pathogenic fungus Candida albicans to switch from a yeast to a hyphal morphology in response to external signals is implicated in its pathogenicity. We used glass DNA microarrays to investigate the transcription profiles of 6333 predicted ORFs in cells undergoing this transition and their responses to changes in temperature and culture medium. We have identified several genes whose transcriptional profiles are similar to those of known virulence factors that are modulated by… CONTINUE READING
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