Transcription patterns of amplified Dytiscus genes coding for ribosomal RNA after injection into Xenopus oocyte nuclei.

@article{Trendelenburg1978TranscriptionPO,
  title={Transcription patterns of amplified Dytiscus genes coding for ribosomal RNA after injection into Xenopus oocyte nuclei.},
  author={Michael F. Trendelenburg and H. Zentgraf and Werner Franke and John Bertrand Gurdon},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1978},
  volume={75 8},
  pages={3791-5}
}
Oocytes of the frog Xenopus were injected with purified circular DNA containing amplified rRNA genes of the water beetle Dytiscus. Nuclear contents of injected oocytes were spread and examined by electron microscopy. Most of the Dytiscus DNA seen in injected nuclei contained regions indensely packed with polymerases and nascent transcripts. Apparently normal, as well as abnormal, patterns of transcription were observed. By this type of experiment, it may become possible to recognize the… CONTINUE READING