Transcription of histone-covered T7 DNA by Escherichia coli RNA polymerase.

@article{Williamson1978TranscriptionOH,
  title={Transcription of histone-covered T7 DNA by Escherichia coli RNA polymerase.},
  author={Patrick J. Williamson and Gary Felsenfeld},
  journal={Biochemistry},
  year={1978},
  volume={17 26},
  pages={5695-705}
}
Purified core histones (H2A, H2B, H3, and H4) and bacteriophage T7 DNA have been reconstituted to form a nucleoprotein complex, and the properties of this complex as a template for transcription by Escherichia coli RNA polymerase have been studied. At low ionic strength, RNA chain elongation rates are slow, and the chains produced even after long incubation… CONTINUE READING